Figure 2

Cytokine intoxication as a model of cell apoptosis and predict of schizophrenia - like affective disorders

Elena Viktorovna Drozdova*

Published: 20 December, 2021 | Volume 5 - Issue 1 | Pages: 038-040

aaai-aid1028-g002

Figure 2:

Displays the mutual influence of serotonergic and rennin angiotensin systems on triggering a cascade of both apoptotic and anti- apoptotic reactions. Starting with serotonin release and further causing release of aldosterone, Ang2 and glucose that increases the amount of prorenin and consequently activates rennin / prorenin receptors. The result is the quantitative and qualitative increase of rennin receptors. Moreover, activated rennin receptors can trigger MAPK cascade that in the presence of pathogen agents (like SARS-CoV2) can cause active cytokine reaction in both directions.

Read Full Article HTML DOI: 10.29328/journal.aaai.1001028 Cite this Article Read Full Article PDF

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