Abstract

Editorial

Interplay between asthma and gastroesophageal reflux disease: A controversial issue

Yiannakopoulou Eugenia*

Published: 05 March, 2018 | Volume 2 - Issue 1 | Pages: 006-007

Gastroesophageal reflux disease (GERD) is a quite common disease caused by the reflux of gastric contents into the esophagus and manifested by heartburn and acid regurgitation. Apart from the esophageal manifestations, GERD is implicated in extraesophageal manifestations including pulmonary manifestations i.e. asthma, chronic cough, pneumonia, idiopathic pulmonary fibrosis, otolaryngological manifestations i.e. laryngitis, otitis, polyps, cancer of the larynx, chest pain [1,2]. The relationship between GERD and pulmonary manifestations is quite challenging and ongoing research efforts have focused on the elucidation of the pathogenesis of GERD induced asthma. 

Read Full Article HTML DOI: 10.29328/journal.aaai.1001011 Cite this Article Read Full Article PDF

References

  1. Martinucci I, Albano E, Marchi S, Blandizzi C. Extra-esophageal presentation of gastroesophageal reflux disease: new understanding in a new era. Minerva Gastroenterol Dietol. 2017; 63: 221-234. Ref.: https://goo.gl/AkJgwN
  2. Sidhwa F, Moore A, Alligood E, Fisichella PM. Diagnosis and Treatment of the Extraesophageal Manifestations of Gastroesophageal Reflux Disease. Ann Surg. 2017; 265: 63-67. Ref.: https://goo.gl/2K46qc
  3. Zhang JX, Zhan XB, Bai C, Li Q. Belching, regurgitation, chest tightness and dyspnea: not gastroesophageal reflux disease but asthma. World J Gastroenterol. 2015; 21: 1680-1683. Ref.: https://goo.gl/XXhYQk
  4. Rameschandra S, Acharya V, Kunal, Vishwanath T, Ramkrishna A, et al. Prevalence and Spectrum of Gastro Esophageal Reflux Disease in Bronchial Asthma. J Clin Diagn Res. 2015; 9: OC11-OC14. Ref.: https://goo.gl/KkdsYz
  5. Saber H, Ghanei M. Extra-esophageal manifestations of gastroesophageal reflux disease: controversies between epidemiology and clicnic. Open Respir Med J. 2012; 6: 121-126. Ref.: https://goo.gl/Zu8BTb
  6. Krill JT, Naik RD, Higginbotham T, Slaughter JC, Holzman MD, et al. Association between response to acid-suppression therapy and efficacy of antireflux surgery in patients with Extraesophageal Reflux. Clin Gastroenterol Hepatol. 2017; 15: 675-681. Ref.: https://goo.gl/V9q4GX
  7. Sidwa F, Moore AL, Alligood E, Fisichella PM. Surgical Treatment of Extraesophageal Manifestations of Gastroesophageal Reflux Disease. World J Surg. 2017; 41: 2566-2571. Ref.: https://goo.gl/5aPa2s

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