Abstract

Editorial

Chemo-cytokines network is main target for control of Allergic asthma

Seyyed Shamsadin Athari* and Seyyede Masoume Athari

Published: 25 January, 2018 | Volume 2 - Issue 1 | Pages: 001-002

Asthma is a chronic respiratory disease which characterized by recurrent airflow obstruction, wheezing, chest tightness and coughing. Management of allergic asthma especially in children, is main problem for industrial world. Immunological factors have critical role in pathogenesis of allergic asthma. Cytokines as major controller of immune system, are important in this reaction. Allergic asthma is a disease with symptoms: eosinophilic inflammation, mucus hyper secretion, airway obstruction, airways hyperresponsivness, IgE high level production, smooth muscle spasm. Cytokines have main and complicated role in pathophysiology of allergic asthma.

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References

  1. Athari SS, Pourpak Z, Folkerts G, Garssen J, Moin M, et al. Conjugated Alpha-Alumina nanoparticle with vasoactive intestinal peptide as a Nano-drug in treatment of allergic asthma in mice. Eur J Pharmacol. 2016; 791: 811-820. Ref.: https://goo.gl/gWvMKn
  2. Conroy DM, Williams TJ. Eotaxin and the attraction of eosinophils to the asthmatic lung. Respir Res. 2001; 2: 150-156. Ref.: https://goo.gl/njPKd2
  3. Farjadian S, Moghtaderi M, Kalani M, Gholami T, Hosseini Teshnizi S. Effects of omega-3 fatty acids on serum levels of T-helper cytokines in children with asthma. Cytokine. 2016; 85: 61-66. Ref.: https://goo.gl/LDMXkk
  4. Schuh JM, Blease K, Kunkel SL, Hogaboam CM. Chemokines and cytokines: axis and allies in asthma and allergy. Cytokine Growth Factor Rev. 2003; 14: 503-510. Ref.: https://goo.gl/RYLy4q
  5. Ravensberg AJ, Ricciardolo FL, van Schadewijk A, Rabe KF, Sterk PJ, et al. Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge. J Allergy Clin Immunol. 2005; 115: 779-785. Ref.: https://goo.gl/oPK7PY

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